蔡建鈞(Henry J Tsai)
姓名 蔡建鈞(Henry J Tsai)
學歷 美國密西根州立大學 生物化學所 博士
現職 亞洲大學食品營養保健生技學系 副教授
電子郵件
分機 04-23323456#20047
研究室 HB47
專長 代謝營養、生理化學、原生質化學、酵素學、流感病毒
教師歷程檔案 教師歷程檔案
教師在校時程表 在校時程表
年度 論文名稱
2024 蔡政道(Jeng-Dau Tsai), 血糖水平的微調-第2 型糖尿病的口服藥物的機制與療法, 台灣營養學會雜誌, 2024
2018 Inactivation of Protein Tyrosine Phosphatase 1B (PTP1B) Activity by the Aqueous Partition of Guava Leaf Extract, JOURNAL OF PHARMACY AND PHARMACOLOGY, vol.6 no.2018 pp.890-906, 2018
2017 宣崇慧(CHUNG-HUI HSUAN)、蔡建鈞(Henry J Tsai)*、RHONA STAINTHORP, The Role of Phonological and Orthographic Awareness in Learning to Read among Grade 1 and 2 Students in Taiwan, APPLIED PSYCHOLINGUISTICS, 2017
2016 Kai-Li Liu、蔡建鈞(Henry J Tsai)、Haw-Wen Chen(Haw-Wen Chen)*, Docosahexaenoic acid inhibits inflammation via free fatty acid receptor FFA4, disruption of TAB2 interaction with TAK1/TAB1 and downregulation of ERK-dependent Egr-1 expression in EA.hy926 cells, MOLECULAR NUTRITION & FOOD RESEARCH, vol.60 no.2 pp.430-443, 2016
2016 宣崇慧(Chung-Hui Hsuan)*、蔡建鈞(Henry J Tsai), 學前識字困難高危險群幼兒之鑑別:學前教師評定搭配認知測驗兩階段篩選機制區辨效能之檢驗, 特殊教育研究學刊/Bulletin of Special Education, vol.41 no.2 pp.29-58, 2016
2016 蔡政道(Jeng-Dau Tsai)*、蔡建鈞(Henry J Tsai), Risk of stroke in patients with mycosis fungoides: A nationwide population-based cohort study, International Journal of Stroke, vol.11 no.4 pp.NP48-NP49, 2016
2015 蔡建鈞(Henry J Tsai), Vilsmeier reagent initialed sequential one-pot multicomponent synthesis of N,O-disubstituted glycolamides as dipeptidyl peptidase 4 inhibitors, TETRAHEDRON, vol.71 pp.6749-6758, 2015
2015 林俊義(Chien-Yih Lin)、蔡建鈞(Henry J Tsai)*, Bioconversion of Banana Pseudostem Fiber to Ethanol: Optimization of Acid Pretreatment Conditions and Fermentation Yeast Selection, ASIAN JOURNAL OF CHEMISTRY, vol.3 no.4 pp.333-342, 2015
2015 蔡建鈞(Henry J Tsai), Subacute necrotizing encephalomyelopathy (Leigh syndrome) in pediatric patients: a retrospective study, International Journal of Biological Sciences, vol.3 no.11 pp.3015-3020, 2015
2015 蔡建鈞(Henry J Tsai), Association between the growth rate of subependymal giant cell astrocytoma and age in patients with tuberous sclerosis complex, CHILDS NERVOUS SYSTEM, vol.9, 2015
2015 蔡政道(Jeng-Dau Tsai)、蔡建鈞(Henry J Tsai)、Ji-Nan Sheu(Ji-Nan Sheu)*, Recurrent Childhood Stroke-like Episodes, Acta Neurologica Taiwanica, vol.24 no.4 pp.133-134, 2015
2014 Li-Ya Wang、蔡建鈞(Henry J Tsai)、Hui-Yi Lin、Kimiyoshi Kaneko、Fen-Ying Cheng、Hsin-Siao Shih、Fung Fuh Wong(Fung Fuh Wong)*、Jiann-Jyh Huang, One-flask synthesis of 1,3,5-trisubstituted 1,2,4- triazoles from nitriles and hydrazonoyl chlorides via 1,3-dipolar cycloaddition, RSC Advances, vol.4 no.0 pp.14125-14220, 2014
2014 蔡建鈞(Henry J Tsai), Comparison of the Detection Rates of RT-PCR and Virus Culture Using a Combination of Specimens from Multiple Sites for Enterovirus-Associated Encephalomyelitis during Enterovirus 71 Epidemic, JAPANESE JOURNAL OF INFECTIOUS DISEASES, vol.67 pp.333-338, 2014
2013 Chun-Hsi Chang、蔡建鈞(Henry Jan-Jen Tsai)、Yu-Ying Huang、Hui-Yi Lin、Li-Ya Wang、Tian-Shung Wu、Fung Fuh Wong(Fung Fuh Wong)*, Selective synthesis of pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl) formamide, or N-(1H-pyrazol-5-yl)formamidine derivatives from N-1-substituted-5-aminopyrazoles with new Vilsmeier-type reagents, TETRAHEDRON, vol.69 no.0 pp.1378-1386, 2013
2013 蔡建鈞(Henry J Tsai), Rhubarb inhibits hepatocellular carcinoma cell metastasis via GSK-3-b activation to enhance protein degradation and attenuate nuclear translocation of b-catenin, FOOD CHEMISTRY, vol.138 no.1 pp.278-285, 2013
2012 蔡建鈞(Henry Jan-Jen Tsai)、齊俐安(Li-Ann Chi)、陳鈴津(Alice L Yu), Monoclonal Antibodies Targeting the Synthetic Peptide Corresponding to the Polybasic Cleavage Site on H5N1 Influenza Hemagglutinin, JOURNAL OF BIOMEDICAL SCIENCE, 2012
2010 Shan-Yen Chou、蔡建鈞(Henry Jan-Jen Tsai)*, Regioselective Synthesis of 3-(1H-indol-3-yl)-5-(1H-indole-3-carbonyl)-4-hydroxyfuroic Acids: A Route to Hydroxyfuroic Acid Based Insulin Receptor Activators, DRUG DEVELOPMENT RESEARCH, vol.71 no.0 pp.1-12, 2010
2009 蔡建鈞(Henry Jan-Jen Tsai)*、ShanYen Chou, A novel hydroxyfuroic acid compound as an insulin receptor activator - structure and activity relationship of a prenylindole moiety to insulin receptor activation., JOURNAL OF BIOMEDICAL SCIENCE, vol.16 no.68 pp.1-12, 2009
2008 蔡建鈞(Henry J Tsai)*、Shan-Yen Chou、SH Chuang、CC Chen、FL Hsu, A Novel Orally Active Sulfonamide Compound Dipeptidyl Peptidase IV Inhibitor: Structure and Activity Relationship of Arylsulfonamide to Dipeptidyl Peptidase IV Inhibition, DRUG DEVELOPMENT RESEARCH, vol.69 no.0 pp.514-519, 2008
2007 蔡建鈞(Henry J Tsai)*, Function of interdomain alpha-helix in human brain hexokinase: covalent linkage and catalytic regulation between N- and C-terminal halves, JOURNAL OF BIOMEDICAL SCIENCE, vol.14 no.2 pp.195-202, 2007
2006 蔡建鈞(Henry J Tsai)、Shan-Yen Chou、Frank Kappler、Michael L Schwartz、Annette M Tobia, A New Inhibitor for Fructosamine 3-Kinase (Amadorase), DRUG DEVELOPMENT RESEARCH, vol.67 no.0 pp.448-455, 2006
2005 D. Andrew Skaff、Chang Sup Kim、蔡建鈞(Henry J Tsai)、Richard B. Honzatko(Richard B. Honzatko)*、Herbert J Fromm, Glucose 6-phosphate release of wild-type and mutant human brain hexokinases from mitochondria, JOURNAL OF BIOLOGICAL CHEMISTRY, vol.280 no.46 pp.38403-38409, 2005
1999 蔡建鈞(Henry J Tsai)*, Functional Organization and Evolution of Mammalian Hexokinases: Mutations That Caused the Loss of Catalytic Activity in N-terminal Halves of Type I and Type III Isozymes, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, vol.369 no.1 pp.149-159, 1999
Chin chu Chen、Henry Tsai(Henry Tsai)*, Tinkering with the Glucose Homeostasis - Oral Therapies for Type 2 Diabetes Mellitus, Open Medicine
發表日期 論文名稱
2011.08 蔡建鈞(Henry Jan-Jen Tsai)、嚴瑋莉(WeiLi Yan)、陳鈴津(Alice Yu), Hypoglycemic Efficacy of Guava Leaf Extract in Vivo , 9th International Conference: Functional Food Components in Health and Disease, Aug. 2011, University of San Diego, CA, USA
2011.03 Extracellular Proteases: A Crossroad between Diabetes Mellitus and Influenza A Virus , 第四屆中國醫藥大學暨亞洲大學生物科技研討會, Mar. 2011, 中國醫藥大學 B1國際會議廳
2010.03 Development of Hydroxyfuroic Acids as an Insulin Receptor Activators (IRA) , 第三屆中國醫藥大學暨亞洲大學生物科技研討會, Mar. 2010, 亞洲大學國際會議廳
2009.06 蔡建鈞(Henry Jan-Jen Tsai)、鄒先岩、徐鳳麟, A New Sulfonamide Compound as an Orally Active Dipeptidyl Peptidase IV Inhibitor – Structure and Activity Relationship of Arylsulfonamide to Dipeptidyl Peptidase IV Inhibition , 台灣藥學會藥物化學研討會 , Jun. 2009, 南投縣溪頭台大實驗林
計畫名稱 參與人 計畫期間
Determination of the 50% hypoglycemic effect dose (hypoglycemic ED50) of water soluble fraction or hot water extract of guava leaf in C57BL mice. (20110726155555) 2011.07 ~ 2011.08
探討以對稱模式解釋哺乳類六碳醣激酶之催化與抑制之機制 (20110421125437) 2011.03 ~ 2012.02
Isolation and identification of the hydrophilic component that is capable of inhibiting protein tyrosine phosphatase (PTP)-1b enzymatic activity in the water soluble fraction of guava leaf extract (20110726155304) 2010.07 ~ 2010.08
呋喃甲酸化合物對胰島素受體訊息傳遞機制的影響研究 (20110421125302) 蔡建鈞(Henry Jan-Jen Tsai) 2010.01 ~ 2010.12
Efficacy of monoclonal antibody targeting the hemagglutinin polybasic cleavage site of H5N1 avian influenza virus (20110726155111) 蔡建鈞(Henry Jan-Jen Tsai) 2009.07 ~ 2009.08
芭樂心葉安全生產栽培體系及其降血糖功效之研究計畫 (20110421125019) 蔡建鈞(Henry Jan-Jen Tsai)、蔡志濃 2009.01 ~ 2009.12
Titration and characterization of monoclonal antibodies specific to H5N1 virus (20110726154918) 蔡建鈞(Henry Jan-Jen Tsai) 2008.07 ~ 2008.08
年度 名稱 全部作者
098 芭樂心葉茶降血糖功效之研究 張嘉婷