蔡建鈞
姓名 蔡建鈞
學歷 美國密西根州立大學 生物化學所 博士
現職 亞洲大學食品營養保健生技學系 副教授
電子郵件 henrytsai@asia.edu.tw
分機 04-23323456#20047
研究室 HB47
專長 代謝營養、生理化學、原生質化學、酵素學、流感病毒
教師歷程檔案 教師歷程檔案
教師在校時程表 在校時程表
年度 論文名稱
2018 Inactivation of Protein Tyrosine Phosphatase 1B (PTP1B) Activity by the Aqueous Partition of Guava Leaf Extract, JOURNAL OF PHARMACY AND PHARMACOLOGY, vol.6 no.2018 pp.890-906, 2018
2017 宣崇慧(CHUNG-HUI HSUAN)、蔡建鈞(Henry J Tsai)*、RHONA STAINTHORP, The Role of Phonological and Orthographic Awareness in Learning to Read among Grade 1 and 2 Students in Taiwan, APPLIED PSYCHOLINGUISTICS, 2017
2016 Kai-Li Liu、蔡建鈞(Henry J Tsai)、Haw-Wen Chen(Haw-Wen Chen)*, Docosahexaenoic acid inhibits inflammation via free fatty acid receptor FFA4, disruption of TAB2 interaction with TAK1/TAB1 and downregulation of ERK-dependent Egr-1 expression in EA.hy926 cells, MOLECULAR NUTRITION & FOOD RESEARCH, vol.60 no.2 pp.430-443, 2016
2016 宣崇慧(Chung-Hui Hsuan)*、蔡建鈞(Henry J Tsai), 學前識字困難高危險群幼兒之鑑別:學前教師評定搭配認知測驗兩階段篩選機制區辨效能之檢驗, 特殊教育研究學刊/Bulletin of Special Education, vol.41 no.2 pp.29-58, 2016
2016 蔡政道(Jeng-Dau Tsai)*、蔡建鈞(Henry J Tsai), Risk of stroke in patients with mycosis fungoides: A nationwide population-based cohort study, International Journal of Stroke, vol.11 no.4 pp.NP48-NP49, 2016
2015 蔡建鈞(Henry J Tsai), Vilsmeier reagent initialed sequential one-pot multicomponent synthesis of N,O-disubstituted glycolamides as dipeptidyl peptidase 4 inhibitors, TETRAHEDRON, vol.71 pp.6749-6758, 2015
2015 林俊義(Chien-Yih Lin)、蔡建鈞(Henry J Tsai)*, Bioconversion of Banana Pseudostem Fiber to Ethanol: Optimization of Acid Pretreatment Conditions and Fermentation Yeast Selection, ASIAN JOURNAL OF CHEMISTRY, vol.3 no.4 pp.333-342, 2015
2015 蔡建鈞(Henry J Tsai), Subacute necrotizing encephalomyelopathy (Leigh syndrome) in pediatric patients: a retrospective study, International Journal of Biological Sciences, vol.3 no.11 pp.3015-3020, 2015
2015 蔡建鈞(Henry J Tsai), Association between the growth rate of subependymal giant cell astrocytoma and age in patients with tuberous sclerosis complex, CHILDS NERVOUS SYSTEM, vol.9, 2015
2015 蔡政道(Jeng-Dau Tsai)、蔡建鈞(Henry J Tsai)、Ji-Nan Sheu(Ji-Nan Sheu)*, Recurrent Childhood Stroke-like Episodes, Acta Neurologica Taiwanica, vol.24 no.4 pp.133-134, 2015
2014 Li-Ya Wang、蔡建鈞(Henry J Tsai)、Hui-Yi Lin、Kimiyoshi Kaneko、Fen-Ying Cheng、Hsin-Siao Shih、Fung Fuh Wong(Fung Fuh Wong)*、Jiann-Jyh Huang, One-flask synthesis of 1,3,5-trisubstituted 1,2,4- triazoles from nitriles and hydrazonoyl chlorides via 1,3-dipolar cycloaddition, RSC Advances, vol.4 no.0 pp.14125-14220, 2014
2014 蔡建鈞(Henry J Tsai), Comparison of the Detection Rates of RT-PCR and Virus Culture Using a Combination of Specimens from Multiple Sites for Enterovirus-Associated Encephalomyelitis during Enterovirus 71 Epidemic, JAPANESE JOURNAL OF INFECTIOUS DISEASES, vol.67 pp.333-338, 2014
2013 Chun-Hsi Chang、蔡建鈞(Henry Jan-Jen Tsai)、Yu-Ying Huang、Hui-Yi Lin、Li-Ya Wang、Tian-Shung Wu、Fung Fuh Wong(Fung Fuh Wong)*, Selective synthesis of pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl) formamide, or N-(1H-pyrazol-5-yl)formamidine derivatives from N-1-substituted-5-aminopyrazoles with new Vilsmeier-type reagents, TETRAHEDRON, vol.69 no.0 pp.1378-1386, 2013
2013 蔡建鈞(Henry J Tsai), Rhubarb inhibits hepatocellular carcinoma cell metastasis via GSK-3-b activation to enhance protein degradation and attenuate nuclear translocation of b-catenin, FOOD CHEMISTRY, vol.138 no.1 pp.278-285, 2013
2012 蔡建鈞(Henry Jan-Jen Tsai)、齊俐安(Li-Ann Chi)、陳鈴津(Alice L Yu), Monoclonal Antibodies Targeting the Synthetic Peptide Corresponding to the Polybasic Cleavage Site on H5N1 Influenza Hemagglutinin, JOURNAL OF BIOMEDICAL SCIENCE, 2012
2010 Shan-Yen Chou、蔡建鈞(Henry Jan-Jen Tsai)*, Regioselective Synthesis of 3-(1H-indol-3-yl)-5-(1H-indole-3-carbonyl)-4-hydroxyfuroic Acids: A Route to Hydroxyfuroic Acid Based Insulin Receptor Activators, DRUG DEVELOPMENT RESEARCH, vol.71 no.0 pp.1-12, 2010
2009 蔡建鈞(Henry Jan-Jen Tsai)*、ShanYen Chou, A novel hydroxyfuroic acid compound as an insulin receptor activator - structure and activity relationship of a prenylindole moiety to insulin receptor activation., JOURNAL OF BIOMEDICAL SCIENCE, vol.16 no.68 pp.1-12, 2009
2008 蔡建鈞(Henry J Tsai)*、Shan-Yen Chou、SH Chuang、CC Chen、FL Hsu, A Novel Orally Active Sulfonamide Compound Dipeptidyl Peptidase IV Inhibitor: Structure and Activity Relationship of Arylsulfonamide to Dipeptidyl Peptidase IV Inhibition, DRUG DEVELOPMENT RESEARCH, vol.69 no.0 pp.514-519, 2008
2007 蔡建鈞(Henry J Tsai)*, Function of interdomain alpha-helix in human brain hexokinase: covalent linkage and catalytic regulation between N- and C-terminal halves, JOURNAL OF BIOMEDICAL SCIENCE, vol.14 no.2 pp.195-202, 2007
2006 蔡建鈞(Henry J Tsai)、Shan-Yen Chou、Frank Kappler、Michael L Schwartz、Annette M Tobia, A New Inhibitor for Fructosamine 3-Kinase (Amadorase), DRUG DEVELOPMENT RESEARCH, vol.67 no.0 pp.448-455, 2006
2005 D. Andrew Skaff、Chang Sup Kim、蔡建鈞(Henry J Tsai)、Richard B. Honzatko(Richard B. Honzatko)*、Herbert J Fromm, Glucose 6-phosphate release of wild-type and mutant human brain hexokinases from mitochondria, JOURNAL OF BIOLOGICAL CHEMISTRY, vol.280 no.46 pp.38403-38409, 2005
1999 蔡建鈞(Henry J Tsai)*, Functional Organization and Evolution of Mammalian Hexokinases: Mutations That Caused the Loss of Catalytic Activity in N-terminal Halves of Type I and Type III Isozymes, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, vol.369 no.1 pp.149-159, 1999
Chin chu Chen、Henry Tsai(Henry Tsai)*, Tinkering with the Glucose Homeostasis - Oral Therapies for Type 2 Diabetes Mellitus, Open Medicine
發表日期 論文名稱
2011.08 蔡建鈞(Henry Jan-Jen Tsai)、嚴瑋莉(WeiLi Yan)、陳鈴津(Alice Yu), Hypoglycemic Efficacy of Guava Leaf Extract in Vivo , 9th International Conference: Functional Food Components in Health and Disease, Aug. 2011, University of San Diego, CA, USA
2011.03 Extracellular Proteases: A Crossroad between Diabetes Mellitus and Influenza A Virus , 第四屆中國醫藥大學暨亞洲大學生物科技研討會, Mar. 2011, 中國醫藥大學 B1國際會議廳
2010.03 Development of Hydroxyfuroic Acids as an Insulin Receptor Activators (IRA) , 第三屆中國醫藥大學暨亞洲大學生物科技研討會, Mar. 2010, 亞洲大學國際會議廳
2009.06 蔡建鈞(Henry Jan-Jen Tsai)、鄒先岩、徐鳳麟, A New Sulfonamide Compound as an Orally Active Dipeptidyl Peptidase IV Inhibitor – Structure and Activity Relationship of Arylsulfonamide to Dipeptidyl Peptidase IV Inhibition , 台灣藥學會藥物化學研討會 , Jun. 2009, 南投縣溪頭台大實驗林
計畫名稱 參與人 計畫期間
Determination of the 50% hypoglycemic effect dose (hypoglycemic ED50) of water soluble fraction or hot water extract of guava leaf in C57BL mice. (20110726155555) 2011.07 ~ 2011.08
探討以對稱模式解釋哺乳類六碳醣激酶之催化與抑制之機制 (20110421125437) 2011.03 ~ 2012.02
Isolation and identification of the hydrophilic component that is capable of inhibiting protein tyrosine phosphatase (PTP)-1b enzymatic activity in the water soluble fraction of guava leaf extract (20110726155304) 2010.07 ~ 2010.08
呋喃甲酸化合物對胰島素受體訊息傳遞機制的影響研究 (20110421125302) 蔡建鈞(Henry Jan-Jen Tsai) 2010.01 ~ 2010.12
Efficacy of monoclonal antibody targeting the hemagglutinin polybasic cleavage site of H5N1 avian influenza virus (20110726155111) 蔡建鈞(Henry Jan-Jen Tsai) 2009.07 ~ 2009.08
芭樂心葉安全生產栽培體系及其降血糖功效之研究計畫 (20110421125019) 蔡建鈞(Henry Jan-Jen Tsai)、蔡志濃 2009.01 ~ 2009.12
Titration and characterization of monoclonal antibodies specific to H5N1 virus (20110726154918) 蔡建鈞(Henry Jan-Jen Tsai) 2008.07 ~ 2008.08
課程類別 課程代碼 課程名稱 年度
大學日間部 TF310029A 生物化學(一) 111
進修學士班 TF500059A 生物化學(一) 111
大學日間部 TF310101A 營養學(一) 111
大學日間部 TF310103A 營養學實驗 111
大學日間部 TF310122A 病例閱讀 111
進修學士班 TF500075A 公共衛生營養學 111
進修學士班 TF500168A 學輔時間(二) 111
進修學士班 TF500209A 營養代謝 111
年度 名稱 全部作者
098 芭樂心葉茶降血糖功效之研究 張嘉婷