Ya-Chen Yang
Name Ya-Chen Yang
Email yachenyang@asia.edu.tw
Job title Associate Professor
Education Ph.D., Applied Chemistry, Providence University
TEL +886-4-23323456#1839
Lab I525
e-Portfolio http://research.asia.edu.tw/TchEportfolio/index_1/yachenyang
In School Schedule In School Schedule
Year Paper Title
2022 CHUN-KAI FU、蒙美津(Mei-Chin Mong)、CHIEN-CHIH YU、MEI-DUE YANG、王智弘(Wang Zhi-Hong)、楊雅甄(Ya-Chen Yang)、DA-TIAN BAU, Association of Matrix Metallopeptidase-2 Genotypes With Risk of Gastric Cancer in Taiwan, ANTICANCER RESEARCH, vol.42 pp.1749-1755, 2022
2022 李嘉翔(Chun-Che Lin)、楊雅甄(Ya-Chen Yang)、TE-CHUN HSIA、TE-CHUN SHEN、YI-CHENG SHEN、WEN-SHIN CHANG、DA-TIAN BAU(DA-TIAN BAU)*, Association of Interleukin-8 Promoter Genotypes With Taiwan Lung Cancer Risk, ANTICANCER RESEARCH, vol.42 pp.1229-1236, 2022
2022 JEN-SHENG PEI、WEN-SHIN CHANG、PEI-CHEN HSU、CHAO-CHUN CHEN、楊雅甄(Ya-Chen Yang)、SHIH-WEI HSU、DA-TIAN BAU2, Contribution of Cyclin-dependent Kinase Inhibitor 1B Genotypes to Childhood Leukemia Risk, IN VIVO, vol.36 pp.1637-1642, 2022
2022 MENG-FENG WU、LI-HSIOU CHEN、NING-YI HSIA、YI-CHENG SHEN、TE-CHUN SHEN1、Wang Zhi-Hong、楊雅甄(Ya-Chen Yang)、DA-TIAN BAU, Significant Contribution of Interleukin-18 Genotypes to Lung Cancer Risk in Taiwanese, ANTICANCER RESEARCH, vol.42 pp.3381-3387, 2022
2021 羅佳文(Chia-Wen Lo)、Chong-Kuei Lii、Jian-Jhe Hong、Wei-Ting Chuang、楊雅甄(Ya-Chen Yang)、Haw-Wen Chen, Andrographolide inhibits IL-1β release in bone marrow-derived macrophages and monocyte infiltration in mouse knee joints induced by monosodium urate, TOXICOLOGY AND APPLIED PHARMACOLOGY, vol.410 no.1 pp.115341-115341, 2021
2021 Chun-Che Lin、楊雅甄(Ya-Chen Yang)、Chia-Yu Chen、殷湄晶(Mei-chin Yin)*, Combination of s-methyl cysteine and protocatechuic acid provided greater lipid-lowering and anti-inflammatory effects in mice liver against chronic alcohol consumption., Iranian Journal of Basic Medical Sciences, 2021
2021 陳智傑(Chih-Chieh Chen)、Chong-Kuei Lii、Chia-Wen Lo、Yi-Hsueh Lin、楊雅甄(Ya-Chen Yang)、Chin-Shiu Huang、Haw-Wen Chen, 14-Deoxy-11,12-Didehydroandrographolide Ameliorates Glucose Intolerance by Enhancing the LKB1/AMPKα/TBC1D1/ GLUT4 Signaling Pathway and Inducing GLUT4 Expression in Myotubes and Skeletal Muscle of Obese Mice, The American journal of Chinese medicine, vol.49 no.6 pp.1473-1491, 2021
2021 傅茂祖(Mao-Tsu Fuh)、Chin-Chun Tseng、Sin-Min Lee、Chuo-En Tsai、Chih-Hao Lu、楊雅甄(Ya-Chen Yang)、翁豐富(Fung Fuh Wong), Design, synthesis and biological evaluation of glycolamide, glycinamide, and β-amino carbonyl 1,2,4-triazole derivatives as DPP-4 inhibitors, BIOORGANIC CHEMISTRY, vol.114 pp.105049-, 2021
2020 楊雅甄(Ya-Chen Yang)、蒙美津(Mei-Chin Mong)、吳文慈(Wen-Tzu Wu)、王智弘(Wang Zhi-Hong)、殷湄晶(Mei-chin Yin), Phytochemical profiles and anti-diabetic benefits of two edible Amaranthus species, CyTA-Journal of Food, vol.18 no.1 pp.94-101, 2020
2020 Chih-Chieh Chen、Chong-Kuei Lii、Yi-Hsueh Lin、Pei-Hsin Shi、楊雅甄(Ya-Chen Yang)、Chin-Shiu Huang、Haw-Wen Chen, Andrographis paniculata Improves Insulin Resistance in High-Fat Diet-Induced Obese Mice and TNFα-Treated 3T3-L1 Adipocytes, The American journal of Chinese medicine, vol.48 pp.1073-1090, 2020
2020 翁豐富(Fung-Fuh Wong)、楊雅甄(Ya-Chen Yang), Chlorotrimethylsilane promoted one-flask heterocyclic synthesis of 1,2,4- triazoles from nitrilimines: Modeling studies and bioactivity evaluation of LH-21 and Rimonabant analogues, BIOORGANIC CHEMISTRY, vol.104 no.1 pp.104299-104299, 2020
2020 Sin-Min Li、Shuo-En Tsai、Chia-Yin Chiang、Fung-Fuh Wong、楊雅甄(Ya-Chen Yang), New methyl 5-(halomethyl)-1-aryl-1H-1,2,4-triazole-3-carboxylates as selective COX-2 inhibitors and anti-inflammatory agents: Design, synthesis, biological evaluation, and docking study, BIOORGANIC CHEMISTRY, vol.104 no.1 pp.104333-104333, 2020
2019 C. C. Yen、Y. T. Liu、楊雅甄(Ya-Chen Yang)、C. C. Chen、H. W. Chen, Bioavailability of the diterpenoid 14-deoxy-11,12-didehydroandrographolide in rats and up-regulation of hepatic drug-metabolizing enzyme and drug transporter expression, PHYTOMEDICINE, vol.61 pp.152841-152845, 2019
2019 Hung-Chih Lin、Chong-Kuei Lii、Ai-Hsuan Lin、Chien-Chun Li、Chia-Han Tsai、Shiuan-Kai Pan、楊雅甄(Ya-Chen Yang)、Haw-Wen Chen, Docosahexaenoic acid inhibits TNFα-induced ICAM-1 expression by activating PPARα and autophagy in human endothelial cells, FOOD AND CHEMICAL TOXICOLOGY, vol.134 pp.110811-, 2019
2018 楊雅甄(Ya-Chen Yang)、王智弘(Wang Zhi-Hong)、殷湄晶(Mei-chin Yin)*, Content of nitric oxide and glycative compounds in cured meat products-Negative impact upon health, BioMedicine, vol.8 no.2 pp.28-33, 2018
2017 林鴻林(Hung-Chih Lin)*、楊雅甄(Ya-Chen Yang), Andrographolide Inhibits Hypoxia-Induced HIF-1a-Driven Endothelin 1 Secretion by Activating Nrf2/HO-1 and Promoting the Expression of Prolyl Hydroxylases 2/3 in Human Endothelial Cells, Environmental Toxicology, vol.32 no.3 pp.918-930, 2017
2016 楊雅甄(Ya-Chen Yang)、陳暉雯(Haw Wen Chen)*, Docosahexaenoic acid inhibits inflammation via Free Fatty Acid Receptor FFA4, disruption of TAB2 interaction with TAK1/TAB1, and down-regulation of ERK-dependent Egr-1 expression in EA.hy926 cells, MOLECULAR NUTRITION & FOOD RESEARCH, vol.60 pp.430-443, 2016
2015 謝承紘(Cheng-Hong Hsieh)、李傳珍(Chuan-Chen Lee)、楊雅甄(Ya-Chen Yang)*, Hepatotoxic pyrrolizidine alkaloids in Emilia sonchifolia from Taiwan, JOURNAL OF FOOD COMPOSITION AND ANALYSIS, vol.215 pp.1-7, 2015
2014 楊雅甄(Ya-Chen Yang)、謝承紘(Cheng-Hong Hsieh), Authentication of consumer fraud in Taiwanese fish products by molecular trace evidence and forensically informative nucleotide sequencing, FOOD RESEARCH INTERNATIONAL, vol.55 pp.294-302, 2014
2014 楊雅甄(Ya-Chen Yang), Andrographolide inhibits TNFα-induced ICAM-1 expression via suppression of NADPH oxidase activation and induction of HO-1 and GCLM expression through the PI3K/Akt/Nrf2 and PI3K/Akt/AP-1 pathways in human endothelial cells., BIOCHEMICAL PHARMACOLOGY, vol.91 no.1 pp.40-50, 2014
2013 楊雅甄(Ya-Chen Yang), Docosahexaenoic acid inhibition of inflammation is partially via cross-talk betweenNrf2/heme oxygenase 1 and IKK/NF-κB pathways, JOURNAL OF NUTRITIONAL BIOCHEMISTRY, vol.24 pp.204-212, 2013
2012 楊雅甄(Ya-Chen Yang)、Shaw-Tao Lin, Conformational Analysis of trans- 2,11-Dithia-4e,5,6,7e,8,9-hexahydro[3.3]paracyclophane Using VT-NMR, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.59 no.2 pp.373-377, 2012
2012 楊雅甄(Ya-Chen Yang)、謝承紘(Cheng-Hong Hsieh), A unique specification method for processed unicorn filefish products using a DNA barcode marker, FOOD CONTROL, vol.25 no.1 pp.292-302, 2012
2011 楊雅甄(Ya-Chen Yang)、Chong-Kuei Lii、Haw-Wen Chen, Induction of glutathione synthesis and heme oxygenase 1 by the flavonoids butein and phloretin is mediated through the ERK/Nrf2 pathway and protects against oxidative stress, FREE RADICAL BIOLOGY AND MEDICINE, vol.51 pp.2073-2081, 2011
2008 楊雅甄(Ya-Chen Yang)、Shaw-Tao Lin(Shaw-Tao Lin,)*、Wen-Shing Ch, Tetrathiadodeca-hydro[]paracyclophane Complexed with Copper(I) and Silver(I) complexes, JOURNAL OF CHEMICAL RESEARCH-S pp.280-284, 2008
2007 楊雅甄(Ya-Chen Yang), Synthesis and Structural Study ofCopper(I) or Silver(I) Complexes of 2,11-dithia-4,5,6,7,8,9-hexahydro[3.3]-paracyclophanes, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.54 pp.587-594, 2007
2006 李傳珍(Chuan-Chen Lee)、楊雅甄(Ya-Chen Yang), Carbon-13 NMR and PM3 Study on the Substituent Effect of 1-Aryl-3,3-difluoro-2- halocyclopropenes, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.53 pp.915-921, 2006
2005 Preparation and spectroscopic1 study of 13-substituted 2,11-dithiahexahydro[3.3]paracyclophanes, JOURNAL OF CHEMICAL RESEARCH-S pp.708.-717, 2005
2003 楊雅甄(Ya-Chen Yang)、、, Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine riddelliine, TOXICOLOGY LETTERS, vol.145 pp.239--247, 2003
2002 楊雅甄(Ya-Chen Yang), Pyrrolizidine Alkaloids - Tumorigenic Components in Chinese Herbal Medicines and Dietary Supplements, JOURNAL OF FOOD AND DRUG ANALYSIS, vol.10 pp.198-211, 2002
2002 楊雅甄(Ya-Chen Yang), Detection of Riddelliine-Derived DNA Adducts in Blood of Rats Fed Riddelliine, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol.3 pp.1019-1026, 2002
2001 Peter. P. Fu,、Ming W. Chou,、Q. Xia、楊雅甄(Ya-Chen Yang), Genotoxic Pyrrolizidine Alkaloid N-oxides-Mechanism Leading to DNA Adduct Formation and Tumorigenicity., JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGEN, vol.19, 2001
2001 楊雅甄(Ya-Chen Yang), Metabolic Activation Pathways of the Pyrrolizidine Alkaloid, Riddelliine, Leading to DNA Adduct Formation in Vivo, CHEMICAL RESEARCH IN TOXICOLOGY, vol.14 pp.101-109, 2001
2001 楊雅甄(Ya-Chen Yang), Development of a 32P-Postlabelling/HPLC Method for Detection of Dehydroretronecine-Derived DNA Adducts In Vitro and In Vivo;, CHEMICAL RESEARCH IN TOXICOLOGY, vol.14 pp.91-100, 2001
2001 楊雅甄(Ya-Chen Yang), Preparation of Hydroquinone-Containing Polymers by ROMP, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.48 pp.945-948, 2001
Date of Publication Paper Title
2021.06 詹巧羽(Qiao-Yu Zhan)、許羽鎔(Yu-Jung Hsu)、翁韻純(Yun-Chun Weng)、張筱筠(Hsiao-Chuan Chang)、楊雅甄(Ya-Chen Yang), 花蓮澤蘭中肝毒性?咯里西啶生物鹼之檢測 , 2021中亞聯大生物科技研討會, Jun. 2021, 台灣/台中
2021.06 許羽鎔(Yu-Jung Hsu)、詹巧羽(Qiao-Yu Zhan)、楊雅甄(Ya-Chen Yang), 康復力植物中?咯里西啶生物鹼之檢測及定量分析 , 中亞聯大生物科技研討會, Jun. 2021, 台灣/台中
2020.05 莊宏晨、詹巧羽、簡妤庭、楊雅甄(Ya-Chen Yang), 台灣澤蘭中肝毒性?咯里西啶生物鹼之檢測 , 2020 年中國醫藥大學暨亞洲大學生物科技研討會, May. 2020, 台灣/台中
2020.05 翁韻純、許羽鎔、盧映淇、楊雅甄(Ya-Chen Yang), Determination of Hepatotoxic Pyrrolizidine Alklaloids in Adenostemma lavenia (L.) O. Kuntze , 2020 年中國醫藥大學暨亞洲大學生物科技研討會, May. 2020, 台灣/台中
2018.06 衛柏成(Po-Cheng Wei)、楊雅甄(Ya-Chen Yang), Hepatotoxic Pyrrolizidine Alkaloids in Tussilago Farfara L. from Taiwan. , 2018生物醫學國際研討會, Jun. 2018, 中國醫藥大學
2017.06 Identification and Quantitative Analysis of Pyrrolizidine Alkaloids in Crotalaria Verrucosa L. from Taiwan , 2017 BEST Conference & International Symposium, Jun. 2017, National Yunlin University of Science and Technology, Yunlin, Taiwan
2017.05 卓辰陽(Chen-Yang Cho)、衛柏成(Po-Chen Wei)、莊宏晨(Hong-Chen Jhuang)、鄭翎雲(Ling-Yun Cheng)、王懷忻(Hvai-Hsin Wang)、楊雅甄(Ya-Chen Yang), Exploring Hepatotoxic Pyrrolizidine Alkaloids in Crotalaria Verrucosa (L.) , The 10th Biotechnology conference Asia University, May. 2017, Asia University
2015.07 楊雅甄(Ya-Chen Yang)、卓辰陽(Chen-Yang Cho)、邱登慶(Deng-Qing Qiu), Detection of hepatotoxic pyrrolizidine alkaloids in Mimosa pudica by gas chromatography mass spectrometry , 25th Australian and New Zealand Society for Mass Spectrometry and 6th Asia Oceania Mass Spectrometry, Jul. 2015, Australia
2015.07 卓辰陽(Chen-Yang Cho)、邱登慶(Deng-Cing Ciou), Detection of pyrrolizidine alkaloids in Emilia sonchifolia using liquid chromatography, electrospray ionization mass spectrometry - World Congress on Pharmacology, Jul. 2015, Brisbane, Australia
2013.03 林怡諄(Yi-Zhun Lin)、邱登慶(Deng-Qing Qi)、謝承紘(Cheng-Hong Hsieh)、楊雅甄(Ya-Chen Yang), Quantitative Analysis Of Some Pyrrolizidine Alkaloids In Mimosa pudica by Gas Chromatography, Mass Spectrometry;The 6th Joint Conference on Biotechnology Asia University and China Medical University: p63;台中,台灣 - The 6th Joint Conference on Biotechnology, Mar. 2013, Asia University
2011.07 吳浩洋(Hao-Yang Wu)、賴德宏(De-Hong Lai)、邱登慶(Deng-Qing Qiu)、楊雅甄(Ya-Chen Yang), Identification and Quantification of Hepatotoxic Pyrrolizidine Alkaloids in Heliotropium indicum L. , 2011第八屆台灣質譜年會暨學術研討會, Jul. 2011, 台北
2009.09 楊雅甄(Ya-Chen Yang), DETERMINATION OF HEPATOTOXIC PYRROLIZIDINE ALKALOIDS IN EMILIA SONCHIFOLIA BY GC, MS - International Congress of Asian Society of Toxicology, Sep. 2009, Taipei, Taiwan
2008.12 黃少紘(Shao-Hong Huang)、劉彩琳(Cai-Ling Liou)、何寶瑜(Bao-Yu He)、楊雅甄(Ya-Chen Yang), Determination of hepatotoxic pyrrilizidine alkaloids in Tussilago farfara L. by GC, MS - 97年中國化學年會, Dec. 2008, 彰化
Project Title Participator Period
檢測康復力中所含肝毒性?咯里西啶類生物鹼之研究 (MOST 109-2320-B-468-001 -) 楊雅甄(Ya-Chen Yang) 2020.08 ~ 2021.10
中草藥藤紫丹中肝毒性?咯里西啶生物鹼之檢測 (MOST 108-2635-B-468-001 -) 楊雅甄(Ya-Chen Yang) 2019.08 ~ 2020.07
以LC/MS/MS檢測紫背草之?咯啶生物鹼含量和毒性之研究 (NSC102-2313-B-468 -003) 楊雅甄(Ya-Chen Yang) 2013.08 ~ 2014.07
台灣中草藥紫背草之檢測及肝毒性之研究 (101-2313-B-468 -003) 楊雅甄(Ya-Chen Yang) 2012.08 ~ Up to today
食品安全性研究-河魨製品相關之基因定性定量研究與毒素之基因毒理探討 (20110624114730) 楊雅甄(Ya-Chen Yang) 2009.08 ~ 2010.07
Category Course Code Course Title Year
大學日間部 GOG00448A 美容與化妝品新知-4 111
大學日間部 TF310020A 有機化學 111
大學日間部 TF310100A 有機化學實驗 111
大學日間部 TF320111B 學輔時間(四) 111
大學日間部 TF320120A 化妝品調製學實驗 111
大學日間部 TF320120B 化妝品調製學實驗 111
大學日間部 TF320141A 專業實習 111
進修學士班 TF500224A 保健化妝品學 111
Year Research Title Authors
107 款冬花製品與藤紫丹中肝毒性?咯里西啶生物鹼之檢測 衛柏成
106 台灣大葉野百合中所含肝毒性?咯里西啶類生物鹼之研究
102 開發LC/MS/MS檢測紫背中吡咯啶類生物鹼之方法 林怡諄
102 篦麻選育栽培及油脂分析之研究 張世欣
101 以氣相層析質譜儀檢測含羞草中所含肝毒性雙稠?咯啶類生物鹼 賴德宏
100 以GC-MS檢測耳鉤草中所含肝毒性雙稠吡咯啶類生物鹼 吳浩洋
098 以GC-MS檢測康復力中所含肝毒性雙稠吡咯啶類生物鹼 劉彩琳
098 以GC-MS檢測紫背草中所含雙稠吡咯啶類生物鹼 何寶瑜
098 以GC-MS檢測款冬花中所含致癌性之芘咯定生物鹼 黃少紘