Ya-Chen Yang
Name Ya-Chen Yang
Email yachenyang@asia.edu.tw
Job title Associate Professor
Education Ph.D., Applied Chemistry, Providence University
TEL +886-4-23323456#1839
Lab I525
e-Portfolio http://research.asia.edu.tw/TchEportfolio/index_1/yachenyang
In School Schedule https://als.asia.edu.tw/ezfiles/9/1009/img/2298/520353018.pdf
Year Paper Title
2022 李嘉翔(Chun-Che Lin)、楊雅甄(Ya-Chen Yang)、包大?(DA-TIAN BAU)*, Association of Interleukin-8 Promoter Genotypes With Taiwan Lung Cancer Risk, ANTICANCER RESEARCH, vol.42 pp.1229-1236
2021 傅茂祖(Mao-Tsu Fuh)、楊雅甄(Ya-Chen Yang)、翁豐富(Fung Fuh Wong), Design, synthesis and biological evaluation of glycolamide, glycinamide, and β-amino carbonyl 1,2,4-triazole derivatives as DPP-4 inhibitors, BIOORGANIC CHEMISTRY, vol.114 pp.105049-
2021 Chun-Che Lin、楊雅甄(Ya-Chen Yang)、殷湄晶(Mei-chin Yin)*, Combination of s-methyl cysteine and protocatechuic acid provided greater lipid-lowering and anti-inflammatory effects in mice liver against chronic alcohol consumption., Iranian Journal of Basic Medical Sciences
2021 陳智傑(Chih-Chieh Chen)、楊雅甄(Ya-Chen Yang), 14-Deoxy-11,12-Didehydroandrographolide Ameliorates Glucose Intolerance by Enhancing the LKB1/AMPKα/TBC1D1/ GLUT4 Signaling Pathway and Inducing GLUT4 Expression in Myotubes and Skeletal Muscle of Obese Mice, The American journal of Chinese medicine, vol.49 no.6 pp.1473-1491
2021 羅佳文(Chia-Wen Lo)、楊雅甄(Ya-Chen Yang), Andrographolide inhibits IL-1β release in bone marrow-derived macrophages and monocyte infiltration in mouse knee joints induced by monosodium urate, TOXICOLOGY AND APPLIED PHARMACOLOGY, vol.410 no.1 pp.115341-115341
2020 翁豐富(Fung-Fuh Wong)、楊雅甄(Ya-Chen Yang), New methyl 5-(halomethyl)-1-aryl-1H-1,2,4-triazole-3-carboxylates as selective COX-2 inhibitors and anti-inflammatory agents: Design, synthesis, biological evaluation, and docking study, BIOORGANIC CHEMISTRY, vol.104 no.1 pp.104333-104333
2020 翁豐富(Fung-Fuh Wong)、楊雅甄(Ya-Chen Yang), Chlorotrimethylsilane promoted one-flask heterocyclic synthesis of 1,2,4- triazoles from nitrilimines: Modeling studies and bioactivity evaluation of LH-21 and Rimonabant analogues, BIOORGANIC CHEMISTRY, vol.104 no.1 pp.104299-104299
2020 楊雅甄(Ya-Chen Yang), Andrographis paniculata Improves Insulin Resistance in High-Fat Diet-Induced Obese Mice and TNFα-Treated 3T3-L1 Adipocytes, The American journal of Chinese medicine, vol.48 pp.1073-1090
2020 楊雅甄(Ya-Chen Yang)、蒙美津(Mei-Chin Mong)、吳文慈(Wen-Tzu Wu)、王智弘(Wang Zhi-Hong)、殷湄晶(Mei-chin Yin), Phytochemical profiles and anti-diabetic benefits of two edible Amaranthus species, CyTA-Journal of Food, vol.18 no.1 pp.94-101
2019 楊雅甄(Ya-Chen Yang), Docosahexaenoic acid inhibits TNFα-induced ICAM-1 expression by activating PPARα and autophagy in human endothelial cells, FOOD AND CHEMICAL TOXICOLOGY, vol.134 pp.110811-
2019 楊雅甄(Ya-Chen Yang), Bioavailability of the diterpenoid 14-deoxy-11,12-didehydroandrographolide in rats and up-regulation of hepatic drug-metabolizing enzyme and drug transporter expression, PHYTOMEDICINE, vol.61 pp.152841-152845
2018 楊雅甄(Ya-Chen Yang)、王智弘(Wang Zhi-Hong)、殷湄晶(Mei-chin Yin)*, Content of nitric oxide and glycative compounds in cured meat products-Negative impact upon health, BioMedicine, vol.8 no.2 pp.28-33
2017 林鴻林(Hung-Chih Lin)*、楊雅甄(Ya-Chen Yang), Andrographolide Inhibits Hypoxia-Induced HIF-1a-Driven Endothelin 1 Secretion by Activating Nrf2/HO-1 and Promoting the Expression of Prolyl Hydroxylases 2/3 in Human Endothelial Cells, Environmental Toxicology, vol.32 no.3 pp.918-930
2016 楊雅甄(Ya-Chen Yang)、陳暉雯(Haw Wen Chen)*, Docosahexaenoic acid inhibits inflammation via Free Fatty Acid Receptor FFA4, disruption of TAB2 interaction with TAK1/TAB1, and down-regulation of ERK-dependent Egr-1 expression in EA.hy926 cells, MOLECULAR NUTRITION & FOOD RESEARCH, vol.60 pp.430-443
2015 謝承紘(Cheng-Hong Hsieh)、李傳珍(Chuan-Chen Lee)、楊雅甄(Ya-Chen Yang)*, Hepatotoxic pyrrolizidine alkaloids in Emilia sonchifolia from Taiwan, JOURNAL OF FOOD COMPOSITION AND ANALYSIS, vol.215 pp.1-7
2014 楊雅甄(Ya-Chen Yang), Andrographolide inhibits TNFα-induced ICAM-1 expression via suppression of NADPH oxidase activation and induction of HO-1 and GCLM expression through the PI3K/Akt/Nrf2 and PI3K/Akt/AP-1 pathways in human endothelial cells., BIOCHEMICAL PHARMACOLOGY, vol.91 no.1 pp.40-50
2014 楊雅甄(Ya-Chen Yang)、謝承紘(Cheng-Hong Hsieh), Authentication of consumer fraud in Taiwanese fish products by molecular trace evidence and forensically informative nucleotide sequencing, FOOD RESEARCH INTERNATIONAL, vol.55 pp.294-302
2013 楊雅甄(Ya-Chen Yang), Docosahexaenoic acid inhibition of inflammation is partially via cross-talk betweenNrf2/heme oxygenase 1 and IKK/NF-κB pathways, JOURNAL OF NUTRITIONAL BIOCHEMISTRY, vol.24 pp.204-212
2012 楊雅甄(Ya-Chen Yang)、謝承紘(Cheng-Hong Hsieh), A unique specification method for processed unicorn filefish products using a DNA barcode marker, FOOD CONTROL, vol.25 no.1 pp.292-302
2012 楊雅甄(Ya-Chen Yang)、Shaw-Tao Lin, Conformational Analysis of trans- 2,11-Dithia-4e,5,6,7e,8,9-hexahydro[3.3]paracyclophane Using VT-NMR, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.59 no.2 pp.373-377
2011 楊雅甄(Ya-Chen Yang)、Chong-Kuei Lii、Haw-Wen Chen, Induction of glutathione synthesis and heme oxygenase 1 by the flavonoids butein and phloretin is mediated through the ERK/Nrf2 pathway and protects against oxidative stress, FREE RADICAL BIOLOGY AND MEDICINE, vol.51 pp.2073-2081
2008 楊雅甄(Ya-Chen Yang)、Shaw-Tao Lin(Shaw-Tao Lin,)*、Wen-Shing Ch, Tetrathiadodeca-hydro[3.3.3.3]paracyclophane Complexed with Copper(I) and Silver(I) complexes, JOURNAL OF CHEMICAL RESEARCH-S pp.280-284
2007 楊雅甄(Ya-Chen Yang), Synthesis and Structural Study ofCopper(I) or Silver(I) Complexes of 2,11-dithia-4,5,6,7,8,9-hexahydro[3.3]-paracyclophanes, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.54 pp.587-594
2006 李傳珍(Chuan-Chen Lee)、楊雅甄(Ya-Chen Yang), Carbon-13 NMR and PM3 Study on the Substituent Effect of 1-Aryl-3,3-difluoro-2- halocyclopropenes, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.53 pp.915-921
2005 Preparation and spectroscopic1 study of 13-substituted 2,11-dithiahexahydro[3.3]paracyclophanes, JOURNAL OF CHEMICAL RESEARCH-S pp.708.-717
2003 楊雅甄(Ya-Chen Yang)、、, Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine riddelliine, TOXICOLOGY LETTERS, vol.145 pp.239--247
2002 楊雅甄(Ya-Chen Yang), Detection of Riddelliine-Derived DNA Adducts in Blood of Rats Fed Riddelliine, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol.3 pp.1019-1026
2002 楊雅甄(Ya-Chen Yang), Pyrrolizidine Alkaloids - Tumorigenic Components in Chinese Herbal Medicines and Dietary Supplements, JOURNAL OF FOOD AND DRUG ANALYSIS, vol.10 pp.198-211
2001 楊雅甄(Ya-Chen Yang), Preparation of Hydroquinone-Containing Polymers by ROMP, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.48 pp.945-948
2001 楊雅甄(Ya-Chen Yang), Development of a 32P-Postlabelling/HPLC Method for Detection of Dehydroretronecine-Derived DNA Adducts In Vitro and In Vivo;, CHEMICAL RESEARCH IN TOXICOLOGY, vol.14 pp.91-100
2001 楊雅甄(Ya-Chen Yang), Metabolic Activation Pathways of the Pyrrolizidine Alkaloid, Riddelliine, Leading to DNA Adduct Formation in Vivo, CHEMICAL RESEARCH IN TOXICOLOGY, vol.14 pp.101-109
2001 Peter. P. Fu,、Ming W. Chou,、Q. Xia、楊雅甄(Ya-Chen Yang), Genotoxic Pyrrolizidine Alkaloid N-oxides-Mechanism Leading to DNA Adduct Formation and Tumorigenicity., JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGEN, vol.19
Date of Publication Paper Title
2021.06 許羽鎔(Yu-Jung Hsu)、詹巧羽(Qiao-Yu Zhan)、楊雅甄(Ya-Chen Yang), 康復力植物中?咯里西啶生物鹼之檢測及定量分析 , 中亞聯大生物科技研討會, 台灣/台中
2021.06 詹巧羽(Qiao-Yu Zhan)、許羽鎔(Yu-Jung Hsu)、翁韻純(Yun-Chun Weng)、張筱筠(Hsiao-Chuan Chang)、楊雅甄(Ya-Chen Yang), 花蓮澤蘭中肝毒性?咯里西啶生物鹼之檢測 , 2021中亞聯大生物科技研討會, 台灣/台中
2020.05 翁韻純、許羽鎔、盧映淇、楊雅甄(Ya-Chen Yang), Determination of Hepatotoxic Pyrrolizidine Alklaloids in Adenostemma lavenia (L.) O. Kuntze , 2020 年中國醫藥大學暨亞洲大學生物科技研討會, 台灣/台中
2020.05 莊宏晨、詹巧羽、簡妤庭、楊雅甄(Ya-Chen Yang), 台灣澤蘭中肝毒性?咯里西啶生物鹼之檢測 , 2020 年中國醫藥大學暨亞洲大學生物科技研討會, 台灣/台中
2018.06 衛柏成(Po-Cheng Wei)、楊雅甄(Ya-Chen Yang), Hepatotoxic Pyrrolizidine Alkaloids in Tussilago Farfara L. from Taiwan. , 2018生物醫學國際研討會, 中國醫藥大學
2017.06 Identification and Quantitative Analysis of Pyrrolizidine Alkaloids in Crotalaria Verrucosa L. from Taiwan , 2017 BEST Conference & International Symposium, National Yunlin University of Science and Technology, Yunlin, Taiwan
2017.05 卓辰陽(Chen-Yang Cho)、衛柏成(Po-Chen Wei)、莊宏晨(Hong-Chen Jhuang)、鄭翎雲(Ling-Yun Cheng)、王懷忻(Hvai-Hsin Wang)、楊雅甄(Ya-Chen Yang), Exploring Hepatotoxic Pyrrolizidine Alkaloids in Crotalaria Verrucosa (L.) , The 10th Biotechnology conference Asia University, Asia University
2015.07 卓辰陽(Chen-Yang Cho)、邱登慶(Deng-Cing Ciou), Detection of pyrrolizidine alkaloids in Emilia sonchifolia using liquid chromatography, electrospray ionization mass spectrometry - World Congress on Pharmacology, Brisbane, Australia
2015.07 楊雅甄(Ya-Chen Yang)、卓辰陽(Chen-Yang Cho)、邱登慶(Deng-Qing Qiu), Detection of hepatotoxic pyrrolizidine alkaloids in Mimosa pudica by gas chromatography mass spectrometry , 25th Australian and New Zealand Society for Mass Spectrometry and 6th Asia Oceania Mass Spectrometry, Australia
2013.03 林怡諄(Yi-Zhun Lin)、邱登慶(Deng-Qing Qi)、謝承紘(Cheng-Hong Hsieh)、楊雅甄(Ya-Chen Yang), Quantitative Analysis Of Some Pyrrolizidine Alkaloids In Mimosa pudica by Gas Chromatography, Mass Spectrometry;The 6th Joint Conference on Biotechnology Asia University and China Medical University: p63;台中,台灣 - The 6th Joint Conference on Biotechnology, Asia University
2011.07 吳浩洋(Hao-Yang Wu)、賴德宏(De-Hong Lai)、邱登慶(Deng-Qing Qiu)、楊雅甄(Ya-Chen Yang), Identification and Quantification of Hepatotoxic Pyrrolizidine Alkaloids in Heliotropium indicum L. , 2011第八屆台灣質譜年會暨學術研討會, 台北
2009.09 楊雅甄(Ya-Chen Yang), DETERMINATION OF HEPATOTOXIC PYRROLIZIDINE ALKALOIDS IN EMILIA SONCHIFOLIA BY GC, MS - International Congress of Asian Society of Toxicology, Taipei, Taiwan
2008.12 黃少紘(Shao-Hong Huang)、劉彩琳(Cai-Ling Liou)、何寶瑜(Bao-Yu He)、楊雅甄(Ya-Chen Yang), Determination of hepatotoxic pyrrilizidine alkaloids in Tussilago farfara L. by GC, MS - 97年中國化學年會, 彰化
Project Title Participator Period
檢測康復力中所含肝毒性?咯里西啶類生物鹼之研究 (MOST 109-2320-B-468-001 -) 楊雅甄(Ya-Chen Yang) 2020.08 ~ 2021.10
中草藥藤紫丹中肝毒性?咯里西啶生物鹼之檢測 (MOST 108-2635-B-468-001 -) 楊雅甄(Ya-Chen Yang) 2019.08 ~ 2020.07
以LC/MS/MS檢測紫背草之?咯啶生物鹼含量和毒性之研究 (NSC102-2313-B-468 -003) 楊雅甄(Ya-Chen Yang) 2013.08 ~ 2014.07
台灣中草藥紫背草之檢測及肝毒性之研究 (101-2313-B-468 -003) 楊雅甄(Ya-Chen Yang) 2012.08 ~ Up to today
食品安全性研究-河魨製品相關之基因定性定量研究與毒素之基因毒理探討 (20110624114730) 楊雅甄(Ya-Chen Yang) 2009.08 ~ 2010.07
Category Course Code Course Title Year
大學日間部 TF320111B 學輔時間(四) 111
大學日間部 GOG00448A 美容與化妝品新知-4 111
Year Research Title Authors
107 款冬花製品與藤紫丹中肝毒性?咯里西啶生物鹼之檢測 衛柏成
106 台灣大葉野百合中所含肝毒性?咯里西啶類生物鹼之研究
102 篦麻選育栽培及油脂分析之研究 張世欣
102 開發LC/MS/MS檢測紫背中吡咯啶類生物鹼之方法 林怡諄
101 以氣相層析質譜儀檢測含羞草中所含肝毒性雙稠?咯啶類生物鹼 賴德宏
100 以GC-MS檢測耳鉤草中所含肝毒性雙稠吡咯啶類生物鹼 吳浩洋
098 以GC-MS檢測款冬花中所含致癌性之芘咯定生物鹼 黃少紘
098 以GC-MS檢測紫背草中所含雙稠吡咯啶類生物鹼 何寶瑜
098 以GC-MS檢測康復力中所含肝毒性雙稠吡咯啶類生物鹼 劉彩琳